In February 2010, Fowler finished second at the Waste Management Phoenix Open with a score of 15-under-par at the TPC of Scottsdale course. In June, Fowler notched his third PGA Tour runner-up finish at the Memorial Tournament in Dublin, Ohio. Fowler entered the final round in the lead, but shot a 73 to finish behind Justin Rose, who recorded his first PGA Tour victory. This performance took Fowler into the top 50 of the Official World Golf Ranking.

In 2008, Fowler repeated as Sunnehanna Amateur champion. In the first round of the U.S. Open, Fowler shot a −1 (70) and was in a tie for 7th place. He was one of three amateurs to make the cut, along with Derek Fathauer and Michael Thompson. He ended the tournament tied for 60th. In October 2008 Fowler played on the Eisenhower Trophy team that finished second. He was the leading individual player.
THE PLAYERS Championship: After beginning the final round of THE PLAYERS Championship three strokes off the lead, at 7-under 209, played his last six holes in 6-under to post a 6-under 66 and join a three-hole aggregate playoff with 2008 PLAYERS champion Sergio Garcia and Kevin Kisner. Finished birdie-par-birdie-eagle-birdie-birdie on Nos. 13-18 in regulation. Played Nos. 15-18 in a 5-under total of 11 strokes. The four-hole score of 11 set a new single-round low for the final four holes at TPC Sawgrass. Previously, seven players had finished with a score of 12 on the final four holes. When Garcia was eliminated after the aggregate playoff, Fowler and Kisner returned to the famed, par-3 17th for sudden death. Fowler converted a 4-foot, 8-inch putt for birdie to claim the title. Before his back-nine charge, his mother had made her way to the airport to leave town. A text message alerting her to her son's rally resulted in her immediate return to TPC Sawgrass in time to witness the win. With the victory, moved to ninth in the Official World Golf Ranking and No. 7 in The Presidents Cup standings.
A better look at my @cobragolf proto irons…second and third pics are top down view of 8 (40°) and 4 (24°) iron…we started working on these back in January…I wanted an old school look (thin/straight top line and no offset) while keeping the benefits of the sole and weight behind the sweet spot (tungsten plugs) these are all hand milled stainless heads…currently working on a pvd finish for the final version…stay tuned👌
On June 3, 2018, DeChambeau won the Memorial Tournament in Dublin, Ohio, in a sudden-death playoff against Kyle Stanley and An Byeong-hun, after the three finished regulation play tied at −15. After Stanley bogeyed the first hole of sudden death, DeChambeau then proceeded to win with a birdie on the second hole, giving him his second win on the tour.[16]
Frys.com Open: At the Frys.com Open in Scottsdale, Ariz., reached a three-way playoff with Jamie Lovemark and eventual-winner Troy Matteson. Began the final round four strokes behind Matteson, but played his first five holes in 5-under, punctuated by a hole-in-one from 211 yards at the par-3 fifth hole. After finishing T2 in the playoff, he had recorded all eight of his professional rounds in the 60s. Thanks to the T7 in Las Vegas at the Justin Timberlake Shriners Hospitals for Children Open and T2 finish at Grayhawk GC, he surpassed No. 150 from the 2008 money list, earning special temporary membership on TOUR for the remainder of the season.

BMW Championship: After entering the final round of the BMW Championship in a second-place tie with Jason Day (five strokes behind Marc Leishman), recorded a 4-under 67 to finish T2, his 11th career runner-up on the PGA TOUR. Week was highlighted by a career-best, six consecutive birdies in the first round on Nos. 12-17. Chipped in from 64 feet on the 17th.
Waste Management Phoenix Open: Won fifth PGA TOUR title at the Waste Management Phoenix Open in his 220th career start at the age of 30 years, 1 month, 21 days. Began the final round with a four-shot lead and won by two strokes after recording a double bogey and triple bogey en route to a closing 3-over 74. Became the first player since 1983 to win with both a double bogey and triple bogey or worse in the final round. Triple bogey came at No. 11 at TPC Scottsdale after he chipped his ball into the water and received an additional penalty when the ball rolled back into the water after he had placed it back into play. Marked the second time of seven occasions he converted a 54-hole lead to victory.
“The switch was very easy. Even though he had won early in the year with another driver, he was not driving it good at all. He is very loyal to our team and our products that he came to us to find a new driver. He instantly loved the look of the Z 585 and once we started testing the numbers were exactly what he was looking for. His main comment about the driver is how his misses are minimal and he can hit all the shots he wants to.”
“I was literally thinking I’d need surgery but I talked to Greg, he was like no, no, no, don’t do any of that, we’re going to teach your body to tolerate the force. Usually when ligaments get torn or bones get broken or whatever it’s because the muscles aren’t functioning properly, so thats what I’ve been doing.” He’s been focusing on exercises that get him into “extreme positions of rotations and flexions” at which point he adds weight to build mental and physical tolerance in those positions.
THE PLAYERS Championship: A week after collecting his first PGA TOUR victory, nearly became the first player since David Duval (1997) to post first two TOUR victories in back-to-back weeks, finishing T2 at THE PLAYERS, two strokes behind winner Matt Kuchar. Holed a birdie attempt from 21 feet, 7 inches on the par 3 17th in the final round to move to 11-under but couldn't convert a 7-foot, 7-inch birdie on No. 18 that would have given him the clubhouse lead at 12-under. Recorded his fifth career runner-up finish on TOUR in his 73rd start. His T2 performance came in his third start at THE PLAYERS and first in which he made the 36-hole cut. Moved into contention with a 66 in the third round, a career low at TPC Sawgrass. Entered the final round three shots off the 54-hole pace.
Enjoyed a stellar rookie season, with seven top-10 finishes and a 32nd-place finish in the FedExCup standings that led to him winning PGA TOUR Rookie of the Year honors. Finished inside the top 30 on the money list to qualify for the Masters and the U.S. Open. Played in first three Playoff events, slipping from 21st to 32nd and out of the TOUR Championship.

In June 2015, he became the first SMU Mustang to win the NCAA individual championship, recording a score of 280 (−8) to win by one stroke.[3] In August, he won the U.S. Amateur title, defeating Derek Bard 7 & 6 in the 36-hole final. He became the fifth player to win both the NCAA and U.S. Amateur titles in the same year, joining Jack Nicklaus (1961), Phil Mickelson (1990), Tiger Woods (1996), and Ryan Moore (2004).[2]
Fowler is one of four golfers in the "Golf Boys" group along with fellow PGA Tour players Ben Crane, Bubba Watson and Hunter Mahan. The Golf Boys released a YouTube video of the song "Oh Oh Oh" on the eve of the 2011 U.S. Open. Farmers Insurance is donating $1,000 for every 100,000 views of the video. The charitable proceeds will support both Farmers and Ben Crane charitable initiatives.[43]

Frys.com Open: At the Frys.com Open in Scottsdale, Ariz., reached a three-way playoff with Jamie Lovemark and eventual-winner Troy Matteson. Began the final round four strokes behind Matteson, but played his first five holes in 5-under, punctuated by a hole-in-one from 211 yards at the par-3 fifth hole. After finishing T2 in the playoff, he had recorded all eight of his professional rounds in the 60s. Thanks to the T7 in Las Vegas at the Justin Timberlake Shriners Hospitals for Children Open and T2 finish at Grayhawk GC, he surpassed No. 150 from the 2008 money list, earning special temporary membership on TOUR for the remainder of the season.
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