Though he appeared in two matches as an un-used substitute for Aston Villa in the 2010–11 season, Lowry continued to be remain out of the first team and in January 2011, Lowry signed for Championship side Sheffield United until the end of the season making his first start for the Blades away at Coventry City a day later. Lowry made eighteen appearances for the Blades but with the club in decline he was unable to prevent them from being relegated at the end of the season.
Immediately after the Masters in mid-April 2016, DeChambeau turned professional and signed a long-term agreement with Cobra-Puma Golf. He made his pro debut days later at the RBC Heritage in South Carolina and tied for fourth, earning over $259,000. The decision to turn professional meant the forfeiture of his exemptions to the U.S. Open at Oakmont and Open Championship at Royal Troon; he qualified his way into the U.S. Open, tied for fifteenth place for over $152,000, and improved his world ranking to 148.
Masters Tournament: Finished runner-up at the Masters, one stroke behind Patrick Reed, for his best result at the event. For the first time in eight starts at Augusta National, recorded four par-or-better rounds (70-72-65-67). Earned his third runner-up in a major (2nd/2018 Masters Tournament, T2/2014 The Open Championship, T2/2014 U.S. Open) and third top-five in the last four (2nd/2018 Masters Tournament, T5/2017 Open Championship, T5/2017 U.S. Open). With third-round 65, was one of just four players to post a bogey-free round during the week (Rory McIlroy/65, Jon Rahm/65, Si Woo Kim/65) with all four occurring in the final round.
All of DeChambeau's irons and wedges are cut to exactly the same length: 37.5 inches (95.3 cm). Their lie and bounce angle are also the same; only the lofts are different. In addition to the single-length concept, his clubs are unusual for their extremely upright lie angle.  DeChambeau keeps the club on the same plane throughout his swing and does not turn his wrists during his swing. In 2011, at the suggestion of his instructor Mike Schy, DeChambeau switched to JumboMax Grips, the largest grips commercially available. The larger grips allow DeChambeau to hold the grips in his palms and not his fingers.
Abu Dhabi HSBC Golf Championship: Held off final-round charges from Thomas Pieters, Rory McIlroy and Henrik Stenson to win the Abu Dhabi HSBC Golf Championship, marking his second European Tour title. The victory was the first at the event by an American since Chris DiMarco won the inaugural event in 2006. Final-round highlights included a holed bunker shot on the eighth hole (which helped propel him to a three-stroke cushion at the turn), a chip-in for birdie on the 17th hole and then a par on the last to hold off Pieters by one stroke.
THE PLAYERS Championship: After beginning the final round of THE PLAYERS Championship three strokes off the lead, at 7-under 209, played his last six holes in 6-under to post a 6-under 66 and join a three-hole aggregate playoff with 2008 PLAYERS champion Sergio Garcia and Kevin Kisner. Finished birdie-par-birdie-eagle-birdie-birdie on Nos. 13-18 in regulation. Played Nos. 15-18 in a 5-under total of 11 strokes. The four-hole score of 11 set a new single-round low for the final four holes at TPC Sawgrass. Previously, seven players had finished with a score of 12 on the final four holes. When Garcia was eliminated after the aggregate playoff, Fowler and Kisner returned to the famed, par-3 17th for sudden death. Fowler converted a 4-foot, 8-inch putt for birdie to claim the title. Before his back-nine charge, his mother had made her way to the airport to leave town. A text message alerting her to her son's rally resulted in her immediate return to TPC Sawgrass in time to witness the win. With the victory, moved to ninth in the Official World Golf Ranking and No. 7 in The Presidents Cup standings.
Waste Management Phoenix Open: Claimed his second runner-up finish at the Waste Management Phoenix Open, one shot behind Hunter Mahan. Had birdie opportunities on the last three holes but unable to catch Mahan. Previously lost in a playoff to Troy Matteson just down the road at Grayhawk GC in the 2009 Frys.com Open. Had he won at TPC Scottsdale, would have become the first Sponsor Exemption to do so since Jason Gore (2005 84 Lumber Classic). Lee Westwood later won in June as a Sponsor Exemption at the St. Jude Classic presented by Smith & Nephew.
Frys.com Open: At the Frys.com Open in Scottsdale, Ariz., reached a three-way playoff with Jamie Lovemark and eventual-winner Troy Matteson. Began the final round four strokes behind Matteson, but played his first five holes in 5-under, punctuated by a hole-in-one from 211 yards at the par-3 fifth hole. After finishing T2 in the playoff, he had recorded all eight of his professional rounds in the 60s. Thanks to the T7 in Las Vegas at the Justin Timberlake Shriners Hospitals for Children Open and T2 finish at Grayhawk GC, he surpassed No. 150 from the 2008 money list, earning special temporary membership on TOUR for the remainder of the season.
The Barclays: Held a one-stroke lead over Patrick Reed after 54 holes at The Barclays in the FedExCup Playoffs, before a double bogey-birdie-bogey finish on Nos. 16-18 resulted in a T7 at 6-under 278 with Jason Kokrak and Ryan Moore. Fowler went bogey free at Bethpage Black from the 10th hole in round one until the 11th hole in the final round, a span of 55 holes. His 55-consecutive holes without a bogey became a personal best on the PGA TOUR, besting 53 from the 2010 Memorial Tournament. This streak also marked the longest recorded in Barclays history since hole information began in 1983. Ian Poulter had the longest with 45 in 2010. The finish marked his third top-10 showing in his last four starts in the event (T9/2013, T9/2014).